Topical Calcineurin Inhibitors List. Both tacrolimus and pimecrolimus block a chemical called calneurin which activates. Calcineurin inhibitors (cnis) are the cornerstone of immunosuppression in sot recipients, but there is little doubt that they contribute significantly to acute kidney injury (aki) and chronic kidney disease (ckd) in this setting.

This activity describes the indications,. Topical calcineurin inhibitors provide a safe alternative for the treatment of sd, as these drugs block the inflammatory cascade involved in the disease process and pose no risk of skin atrophy. There are two types of topical calcineurin inhibitors called tacrolimus ointment (protopic 0.03% and 0.1%) and pimecrolimus cream (elidel).